It's one thing to build a complete connectome of a fly brain. It's quite another to understand how that brain works. "Even if you could incorporate every detail about the imaged neurons and their interactions with one another, the connectome would still represent a single moment in time—devoid of information about how these connections change with experience. 'To me, that is what makes a brain a brain,' says Adriane Otopalik, a group leader at Janelia who previously worked in Marder's lab as a graduate student. 'It seems odd to me to design a model that totally ignores that level of biology.'" The connectome describes the fly's knowledge, but not how it learns or acts.
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