Content-type: text/html ~ Stephen's Web ~ Widely used calcium imaging protocol can lead to spurious results, new paper cautions

Stephen Downes

Knowledge, Learning, Community

This article is a good sample of the work that goes on studying the brain at the biological level. It's a cautionary note, reporting that the use of calcium imaging can produce misleading results. "Some researchers even have a name for the artifacts... We and others have been talking for 15 years about cells getting 'GCaMPed out.'" The article is important because negative findings like this tend to get less press, and when they're not widely distributed, lead to people rediscovering the same problem over and over. It's also a caution against immediately leaping from evidence of physical activity to evidence of neural activity. A lot of stuff happens in the brain.

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Stephen Downes Stephen Downes, Casselman, Canada

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Last Updated: Jul 23, 2024 11:31 a.m.

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